Clinical Laboratory Diagnostics for Mycobacterium tuberculosis

نویسندگان

  • N. Esther Babady
  • Nancy L. Wengenack
چکیده

This chapter highlights current state-of-the-art methods for the detection and identification of Mycobacterium tuberculosis (Mtb) complex in the clinical diagnostic laboratory. Methods discussed include stain and culture which traditionally would have been followed by phenotypic-based identification methods. At this point in time however, molecular methods are considered the gold standard for both the rapid detection of Mtb directly from patient specimens as well as for the identification of Mtb following growth in culture. There are also instances where speciation of Mtb in order to distinguish it from other members of the Mtb complex is clinically important and these will be discussed. In addition, this chapter provides an overview of methods used in the clinical laboratory for Mtb drug resistance testing and suggests what the future might hold for Mtb diagnostics.

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تاریخ انتشار 2012